必须声明标量变量 "@Script_ID"。 生物支架联合干细胞治疗脊髓损伤的研究进展-《赣南医学院学报》

 ZHANG Guanyin-sheng,YE Jun-ming,ZHONG Xing-feng,et al.Research progress of biological scaffold combined with stem cell in the treatment of spinal cord injury[J].,2019,39(12):1247-1253.[doi:10.3969/j.issn.1001-5779.2019.12.016]





Research progress of biological scaffold combined with stem cell in the treatment of spinal cord injury
张观音生1叶军明2钟兴凤3李 艺2胡小莉1康艳敏4
赣南医学院 1.2017级硕士研究生; 2.麻醉系; 3.2016级硕士研究生; 4.2018级硕士研究生, 江西 赣州 341000
ZHANG Guanyin-sheng1 YE Jun-ming2 ZHONG Xing-feng3 LI Yi2 HU Xiao-li1 KANG Yan-min4
Gannan Medical University 1.Post graduate student, Grade 2017; 2.Department of Anesthesiology; 3.Post graduate student, Grade 2016; 4.Post graduate student, Grade 2018, Ganzhou, Jiangxi 341000
脊髓损伤 生物支架 干细胞移植
Spinal cord injury Biological scaffold Stem cell transplantation
脊髓损伤(Spinal cord injury, SCI)是外伤引起的神经损伤性疾病,可以导致损伤部位以下运动功能障碍和感觉丧失。研究发现,将干细胞移植到损伤部位,可以分化为神经元并促进内源性生长因子释放,从而改善SCI。然而,移植的干细胞很少存活。近年,通过生物支架负载干细胞植入到损伤部位,增加了干细胞存活率,促进了SCI的修复。现就生物支架联合干细胞植入在SCI中的治疗进行综述。
Spinal cord injury(SCI)is a neurological injury caused by trauma, which can lead to motor dysfunction and loss of sensation below the injury site. Studies have shown that by stem cell transplantation to the injury site, it can differentiate into neurons and promote the release of endogenous growth factors to improve SCI. However, transplanted stem cells rarely survive. In recent years, implantation of stem cells into the injury site by biological scaffold has increased stem cell viability, and promoted the repair of SCI. Herein, we focused on the treatment of biological scaffold combined with stem cells implantation in SCI.


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[1]袁 萍,郭 兰,兰晓玲,等.中医传统疗法综合康复方案协同康复护理模式对脊髓损伤患者功能恢复影响的研究[J].赣南医学院学报,2018,38(02):171.[doi:10.3969/j.issn.1001-5779.2018.02.024]
 YUAN Ping,GUO Lan,LAN Xiao-ling,et al.Effect of Comprehensive Rehabilitation Program of Traditional Chinese Medicine Combined with Rehabilitation Nursing Mode on Functional Recovery of Patients with Spinal Cord Injury[J].,2018,38(12):171.[doi:10.3969/j.issn.1001-5779.2018.02.024]


基金项目:国家自然科学基金项目(编号:81560375, 81760230); 江西省自然科学基金项目(编号:20171BAB205035)
通信作者:叶军明,男,教授,主任医师,硕士生导师,研究方向:老年医学。E-mail:yjm7798@ sina.com
更新日期/Last Update: 2019-12-30