必须声明标量变量 "@Script_ID"。 Th细胞因子在IgA肾病中的研究进展-《赣南医学院学报》

[1]郭 艳,赵成波,谢富华,等.Th细胞因子在IgA肾病中的研究进展[J].赣南医学院学报,2019,39(10):1063-1066.[doi:10.3969/j.issn.1001-5779.2019.10.024]
 GUO Yan,ZHAO Cheng-bo,XIE Fu-hua,et al.Research advances of Th cytokines in IgA nephropathy[J].,2019,39(10):1063-1066.[doi:10.3969/j.issn.1001-5779.2019.10.024]
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Th细胞因子在IgA肾病中的研究进展()
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《赣南医学院学报》[ISSN:1001-5779/CN:36-1154/R]

卷:
39
期数:
2019年10期
页码:
1063-1066
栏目:
综述
出版日期:
2019-11-24

文章信息/Info

Title:
Research advances of Th cytokines in IgA nephropathy
文章编号:
1001-5779(2019)10-1063-04
作者:
郭 艳1赵成波1谢富华2王润秀3
赣南医学院 1.2017级硕士研究生; 2.基础医学院; 3.第一附属医院,江西 赣州 341000
Author(s):
GUO Yan1 ZHAO Cheng-bo1 XIE Fu-hua2 WANG Run-xiu3
Gannan Medical University 1.Postgraduate Student of Grade 2017; 2.School of Basic Medicine; 3.The First Affiliated Hospital, Ganzhou, Jangxi 341000
关键词:
Th细胞因子 IgAN gd-IgA1 C1GALT1 Cosmc
Keywords:
Th cytokines IgA nephropathy galactose deficient IgA1 C1GALTl Cosmc
分类号:
R692.3
DOI:
10.3969/j.issn.1001-5779.2019.10.024
文献标志码:
A
摘要:
IgA肾病(Immunoglobulin A nephropathy,IgAN)是全世界范围内最常见的原发性肾小球肾炎,也是我国导致慢性肾脏疾病(Chronic kidney disease,CKD)最常见的原因之一。IgAN的发病机制目前仍不清楚,低糖基化IgA1(galactose deficient IgA1,gd-IgA1)以及它形成的免疫复合物在肾小球系膜区沉积是导致IgAN的主要因素。Th细胞因子(T helper cytokines)是由Th细胞分泌的具有广泛生物学活性的小分子多肽。近来,许多研究均表明Th细胞因子广泛参与IgAN。本文就此作一综述。
Abstract:
Immunoglobulin A nephropathy(IgAN)is the most common type of primary glomerulonephritis worldwild and the most common cause of chronic kidney disease(CKD)in China.its pathogenesis is still unclear.The key cause of this disease is the deposition of galactose deficient IgA1 and immune complexes in the glomerular mesangial area.Th cytokines are small molecular polypeptides secreted by Th cells with a wide range of biological activities.Recently, many studies have shown that Th cytokines are widely involved in IgAN.This article gives a review of this.

参考文献/References:

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备注/Memo

备注/Memo:
通信作者:王润秀,女,硕士,副主任医师,研究方向:肾脏病的临床、教学与科研。E-mail:runxiuw2004@163.com
更新日期/Last Update: 2019-11-20